Studies Currently Seeking Volunteers

Study NameInvestigatorCategoryStudy Added
A Randomized Phase III Trial of Platinum Chemotherapy plus Paclitaxel with Bevacizumab and Atezolizumab versus Platinum Chemotherapy plus Paclitaxel and Bevacizumab in Metastatic (stage IVB), Persistent, or Recurrent Carcinoma of the Cervix. (GOG-3030) Destin Black, M.D. Cancer11/8/2021
A Phase 3, randomized, double-blind, adaptive, placebo/paclitaxel-controlled study of AVB-S6-500 in combination with paclitaxel in patients with platinum-resistant recurrent ovarian cancer. (GOG 3059) Destin Black, M.D. Cancer11/8/2021
A randomized, Open-label, Phase 3 Trial of Tisotumab Vedotin vs Investigator’s choice chemotherapy in second or third-line recurrent of metastatic cervical cancer. (GOG-3057) Destin Black, M.D. Cancer11/8/2021
MIRASOL: A randomized, open label, phase 3 study of Mirvetuximab Soravtansine vs. Investigator’s choice of chemotherapy in Platinum-Resistant Advance High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers with high folate receptor-alpha expression. (GOG 3045) Destin Black, M.D. Cancer11/8/2021
A Phase 3, Randomized, Double-Blind Study of Pembrolizumab versus Placebo in Combination with Adjuvant Chemotherapy With or Without Radiotherapy for the Treatment of Newly Diagnosed High-Risk Endometrial Cancer After Surgery With Curative Intent. (GOG-3053) Destin Black, M.D. Cancer11/8/2021
A Phase 3b Study to Evaluate the Safety and Efficacy of Elagolix in Combination with Combined Oral Contraceptives in Premenopausal Women with Documented Endometriosis and Associated Moderate to Severe Pain. (M18-969) Greg Phillips, M.D. Gynecology11/5/2021
Prospective multicenter observational study of patients with relapsed or refractory diffuse large B-cell lymphoma starting second or third-line therapy and not receiving autologous stem cell transplant. (Real-mind) Joyce Feagin, M.D. Lymphoma11/5/2021
Trugraf Long-term Clinical Outcomes Study (TRULO) Neeraj Singh, M.D. Kidney11/5/2021
A phase II, observer-blind, randomized, controlled study to evaluate the immunogenicity and safety of a varicella vaccine at various potencies compared with Varivax, as a first dose, administered in healthy children in their second year of life. (VNS-GSK)   Pediatric11/4/2021
Phase III study to compare MenACYW conjugate vaccine with that of MENVEO when administered concomitantly with routine pediatric vaccines to healthy infants and toddlers in the United States. (LULLABY)   Pediatric11/4/2021
APOL1 Long-term Kidney Transplantation Outcomes Network Neeraj Singh, M.D. Kidney10/20/2021
A Phase 3, Randomized, Observer-Blinded, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine (SARS-CoV-2 rS) with Matrix-M1™ Adjuvant in Adult Participants = 18 Years with a Pediatric Expansion in Adolescents (12 to < 18 Years) (Novavax) Clint Wilson, M.D. COVID10/18/2021
A Phase 2/3 Postexposure Prophylaxis Study of PF-07321332/Ritonavir in Household Contacts of a Patient with COVID-19. (Pfizer 1006) Joseph Bocchini, M.D. COVID10/18/2021
A Master Protocol Assessing the Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Patients with COVID-19 (Regeneron 2067) Joseph Bocchini, M.D. COVID8/13/2020
A Phase 3, Randomized, Double-blind, Multicenter Study of Dostarlimab (TSR-042) plus Carboplatin-paclitaxel versus Placebo plus Carboplatin-paclitaxel in Patients with Recurrent or Primary Advanced Endometrial Cancer Destin Black, M.D. Cancer4/21/2020
A Randomized, Double-Blind, Phase 3 Comparison of Platinum-Based Therapy with TSR-042 and Niraparib Versus Standard of Care Platinum-Based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer (3000-03-005/ENGOT-OV44) Destin Black, M.D. Cancer4/21/2020
D5290C00004-A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Late Preterm and Term Infants (MELODY)   Pediatric4/21/2020
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of Durvalumab Monotherapy or in Combination With Bevacizumab as Adjuvant Therapy in Patients With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation (EMERALD-2)   Cancer4/21/2020
A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Transarterial Chemoembolization (TACE) in Combination with either Durvalumab Monotherapy or Durvalumab plus Bevacizumab Therapy in Patients with Locoregional Hepatocellular Carcinoma   Cancer4/21/2020
Malleable Treatment – the Tactra Erectile Restoration Study Gerard Henry, M.D. Urology4/21/2020
Advances in Biofilm and the Future of Infection Prevention in Prosthetic Urology Gerard Henry, M.D. Urology4/21/2020
Artificial Urinary Sphincter Clinical Outcomes Gerard Henry, M.D. Urology4/21/2020
Post Approval Study of the AcrySof® IQ ReSTOR® Toric IntraOcular Lens Dr. Wyche Coleman, M.D. 4/21/2020
A Phase 2, multi-center, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of topically-applied AG013 for the attenuation of oral mucositis in subjects with cancers of the head and neck receiving concomitant chemoradiation therapy.   Cancer, Radiation Therapy4/21/2020
An intermediate access protocol for selumetinib for treatment of neurofibromatosis type 1 with inoperable, progressive/symptomatic plexiform neurofibromas   Cancer4/21/2020
informCLL: A Disease Registry for Patients with Chronic Lymphocytic Leukemia   Cancer4/21/2020
A Pivotal, Double-blind, Randomized, Placebo-controlled, Multinational Study of SGX942 (Dusquetide) for the Treatment of Oral Mucositis in Patients being Treated with Concomitant Chemoradiation for the Treatment of Squamous Cell Carcinoma of the Head and Neck   Cancer, Radiation Therapy4/21/2020
Phase 3 Randomized Trial Comparing Overall Survival After Photon versus Proton Chemoradiotherapy for Inoperable Stage II-IIIB Non-Small Cell Lung Cancer (NSCLC)   Cancer4/21/2020
Prospective Research Assessments in Multiple Myeloma: An Observational Evaluation (PREAMBLE)   Cancer4/21/2020
A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer (COMPPARE)   Cancer, Radiation Therapy4/21/2020
Evaluation Tracking Project: A Prospective Chart Review of Patients Treated with Radiation Therapy   Cancer, Radiation Therapy4/21/2020
Pivotal, open-label, randomized study of radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 brain metastases from non-small cell lung cancer (NSCLC)   Cancer, Radiation Therapy4/21/2020
A Multicenter, Open-Label, Randomized-Controlled Study of Abemaciclib, a CDK4 & 6 Inhibitor, in Combination with Fulvestrant Compared to Chemotherapy in Women with HR Positive, HER2 Negative Metastatic Breast Cancer with Visceral Metastases   Breast Cancer, Cancer4/21/2020
Phase 2 Double Blind Dose Finding Trial of Bupropion Versus Placebo for Sexual Desire in Women with Breast or Gynecologic Cancer   Cancer4/21/2020
The COVID-19 and Cancer Consortium (CCC19) Registry   Cancer, COVID4/21/2020
Pragmatic Phase III Randomized Trial of Proton versus Photon Therapy for Patients with Non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial   Breast Cancer, Cancer, Radiation Therapy2/17/2017
Observational Study of Patients with Polycythemia Vera in U.S. Clinical Practices (REVEAL)   Cancer11/12/2015